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Anti-Mouse PD-1 Antibody (RMP1-14) (Synonyms: Anti-mouse PD-1 (CD279))
Catalog No. T78269 Copy Product Info
Purity: 98.01%
🥰Excellent
Anti-Mouse PD-1 Antibody (RMP1-14) is an IgG2a antibody inhibitor against mouse PD-1 and can block PD-1/PD-L1 signaling.
Anti-Mouse PD-1 Antibody (RMP1-14)
Copy Product Info🥰Excellent
Catalog No. T78269
Synonyms Anti-mouse PD-1 (CD279)
Anti-Mouse PD-1 Antibody (RMP1-14) is an IgG2a antibody inhibitor against mouse PD-1 and can block PD-1/PD-L1 signaling.
Anti-Mouse PD-1 Antibody
(RMP1-14)
(RMP1-14)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $61 | In Stock | In Stock | |
| 5 mg | $215 | In Stock | In Stock | |
| 10 mg | $378 | In Stock | In Stock | |
| 25 mg | $719 | In Stock | In Stock | |
| 50 mg | $1,030 | In Stock | In Stock | |
| 100 mg | $1,370 | In Stock | In Stock | |
| 200 mg | $2,060 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:98.01%
Color:Transparent
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| Description | Anti-Mouse PD-1 Antibody (RMP1-14) is an IgG2a antibody inhibitor against mouse PD-1 and can block PD-1/PD-L1 signaling. |
| Targets&IC50 | PD-1/PD-L1:4.05 μg/mL, PD-1/PD-L1:1.99 μg/mL |
| In vivo | METHODS: To study the antitumor activity of Anti-Mouse PD-1 Antibody, mice were subcutaneously injected with MC38 (1×10^6) or B16-hCXCR4 (5×10^5). Two weeks later, tumor-bearing mice were intraperitoneally (ip) treated with anti-PD-1 mouse antibody [RMP1-14] (5 mg/kg, twice a week for 2 weeks), Pep R (2 mg/kg, 5 days a week for 2 weeks), or both. RESULTS: Combination therapy (Pep R plus anti-PD-1) reduced the relative tumor volume (RTV) of MC38 by 2.67 times (p=0.038), while anti-PD-1 or Pep R alone did not significantly affect tumor growth. [1] |
| Synonyms | Anti-mouse PD-1 (CD279) |
| Clone | RMP1-14 |
| Reactivity | Mouse |
| Verified Activity | Immobilized Mouse PD-1 Protein (His) (TMPY-00996) at 1 μg/mL can bind Anti-Mouse PD-1 Antibody (RMP1-14). The EC50 is 22.030 ng/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | PDCD1/PD-1/CD279 |
| Molecular Weight | 147.57 kDa |
| Isotype | Mouse IgG2a kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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