Shopping Cart
- Remove All
Your shopping cart is currently empty
Sifalimumab
🥰Excellent
Catalog No. T76760Cas No. 1006877-41-3
Alias MEDI-545, MDX-1103
Sifalimumab (MEDI-545) is a monoclonal antibody that targets IFNα and suppresses abnormal immune activity by binding to interferon-alpha.Sifalimumab is used for the treatment of moderate to severe SLE.
Sifalimumab
Sifalimumab
🥰Excellent
Purity: 100% (SEC-HPLC)
Catalog No. T76760Alias MEDI-545, MDX-1103Cas No. 1006877-41-3
Sifalimumab (MEDI-545) is a monoclonal antibody that targets IFNα and suppresses abnormal immune activity by binding to interferon-alpha.Sifalimumab is used for the treatment of moderate to severe SLE.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $297 | In Stock | |
| 5 mg | $778 | In Stock | |
| 10 mg | $1,230 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Sifalimumab"
Salicylic acid
2-Hydroxybenzoic acid
T064969-72-7
Salicylic acid (2-Hydroxybenzoic acid), a natural compound extracted from Willow bark, is an anti-inflammatory inhibitor of activity cyclooxygenase.
- $33
Size
QTY
Acetaminophen
Cited
Paracetamol, APAP, 4'-Hydroxyacetanilide, 4-Acetamidophenol
T0065103-90-2
Acetaminophen (APAP) is a COX inhibitor that inhibits COX-1 and COX-2 (IC50=113.7/25.8 μM). Acetaminophen has antipyretic and analgesic activity as well as weak anti-inflammatory activity.
- $41
Size
QTY
CitedBismuth Subsalicylate
Bismuth(III) salicylate basic, Bismuth subsalicylat, Bismuth oxysalicylate
T042414882-18-9
Bismuth Subsalicylate (Bismuth subsalicylat) is the active ingredient in the popular medication Pepto-Bismol that is used to treat nausea, heartburn, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract.
- $48
Size
QTY
Paradol
6-paradol, [6]-Gingerone
T711327113-22-0
Paradol ([6]-Gingerone) is a pungent phenolic substance found in ginger and other Zingiberaceae plants, and exhibits a variety of biological activities including anti-cancer, anti-inflammatory, and anti-oxidative activities,neuroprotective Effects.
- $40
Size
QTY
Diclofenac Potassium
Voltfast, CGP-45840B, Cataflam
T647015307-81-0
Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.
- $33
Size
QTY
Diclofenac sodium Cited
GP 45840
T155515307-79-6
Diclofenac sodium (GP 45840) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
- $45
Size
QTY
CitedRevaprazan hydrochloride
YH1885
T2405178307-42-1
Revaprazan hydrochloride (YH1885) is the hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity.
- $37
Size
QTY
Salicylamide
Salamide, 2-Hydroxybenzamide
T000465-45-2
Salicylamide (2-Hydroxybenzamide) is an over-the-counter drug with analgesic and antipyretic properties, which has similar medicinal properties to aspirin. In the over-the-counter pain remedies, Salicylamide is used in combination with both aspirin and caffeine.
- $29
Size
QTY
Ibuprofen Cited
Motrin, Brufen, Advil, (±)-Ibuprofe
T139415687-27-1
Ibuprofen (Advil) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes.
- $45
Size
QTY
CitedGlafenine
Glafenin
T00553820-67-5
Glafenine (Glafenin), a non-narcotic analgesic agent, is a non-steroidal anti-inflammatory drug (NSAID), and widely used for the therapy of pains of various origins.
- $36
Size
QTY
Indomethacin sodium hydrate
Indometacin sodium hydrate
T2234674252-25-8
Indomethacin sodium hydrate (Indometacin sodium hydrate) is an orally active, competitive and reversible COX1/2 inhibitor with potential anti-inflammatory activity in induced migraines, induced gastrointestinal injuries, and may be used in studies of increased intracranial pressure secondary to severe traumatic brain injury and rheumatoid arthritis in adults.
- $40
Size
QTY
trans-Cinnamaldehyde
Phenylacrolein, Cinnamic aldehyde, Cinnamaldehyde, Cinnamal
T3S155314371-10-9
1. trans-Cinnamaldehyde (Phenylacrolein) exhibits excellent anti-inflammatory activities and antidepressant-like effects in stressed mid-aged rats as a COX-2 inhibitor. 2. Cinnamic aldehyde induces apoptosis of CML cells in vitro, down-regulation of the expression and function of BCR-ABL may be one of its most important anti-leukemia mechanisms. 3. Cinnamic aldehyde and cinnamic acid are cardioprotective in a rat model of ischemic myocardial injury, the mechanism is related to anti-oxidative and anti-inflammatory properties.
- $33
Size
QTY
Select Batch
Concentration:5.78 mg/mL
Purity:100% (SEC-HPLC)
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | Sifalimumab (MEDI-545) is a monoclonal antibody that targets IFNα and suppresses abnormal immune activity by binding to interferon-alpha.Sifalimumab is used for the treatment of moderate to severe SLE. |
| In vitro | Attenuating lymphocyte cytotoxicity co-cultured with U-87MG, sifalimumab is effective at concentrations ranging from 3 to 36 μg/well when applied for 72 hours[1]. |
| In vivo | Treatment with sifalimumab at doses of 30 mg/kg (subcutaneous injection) and 3 μg/g demonstrates a therapeutic effect and attenuates lymphocyte infiltration[1]. |
| Alias | MEDI-545, MDX-1103 |
| Molecular Weight | 144.24 kDa |
| Cas No. | 1006877-41-3 |
Storage & Solubility Information
| Storage | store at low temperature | store at -80°C | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Sifalimumab | purchase Sifalimumab | Sifalimumab cost | order Sifalimumab | Sifalimumab in vivo | Sifalimumab in vitro | Sifalimumab molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.