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ALK
Cat.No. Product Name Information Area
T4071 TPX-0005 TPX-0005 is a potent ALK/ROS1/TRK inhibitor, with IC50 of 5.3 nM, 1.01 nM, 1.26 nM an... Cancer
T4015 HG-14-10-04 HG-14-10-04 is a potent and specific ALK inhibitor with IC50 of 20 nM. IC50 value: 20... Others
T3550 Ensartinibnew Ensartinib, also known as X-396, is an orally available small molecule inhibitor of t... Cancer
T3621 Brigatinibnew Brigatinib is an investigational cancer medicine showing promise in clinical trials a... Cancer
T3041 ALK inhibitor 2 ALK inhibitor 2 is a novel and selective inhibitor for the ALK kinase. Cancer
T3079 GSK1838705A GSK1838705A is a potent IGF-1R inhibitor with IC50 of 2.0 nM, modestly potent to IR a... Cancer
T3059 AP26113 AP26113 is a potent ALK inhibitor with IC50 of 0.62 nM in a cell-free assay, demonstr... Cancer
T3031 A 83-01 A 83-01 is a selective inhibitor of TGF-β type I receptor ALK5 kinase, type I activin... Immunology
T2809 Fangchinoline Extracted from Stephania tetrandra S. Moore;Store the product in sealed,cool and dry ... Cardiovascular System
T2655 CEP-37440 CEP-37440 is a novel potent and selective Dual FAK/ALK inhibitor with IC50 s of 2.3 n... Immunology
T2641 KRCA-0008 KRCA-0008 is a potent and selective ALK/Ack1 inhibitor with IC50 of 12 nM/4 nM for AL... Immunology
T2491 AZ5104 AZ5104, the demethylated metabolite of AZD-9291, is a potent EGFR inhibitor with IC50... Cancer
T2465 PF-562271 PF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 ... Other
T2462 SB-505124 SB505124 is a selective inhibitor of TGFβR for ALK4, ALK5 with IC50 of 129 nM and 47 ... Immunology
T2449 D4476 D 4476 is a potent, selective, and cell-permeant CK1 (casein kinase 1) inhibitor with... Metabolism system
T2314 PF 431396 PF-431396 is a dual PYK2/FAK inhibitor with IC50 of 11 nM and 2 nM, respectively. Other
T2251 NVP-TAE 684 TAE684 (NVP-TAE684) is a potent and selective ALK inhibitor with IC50 of 3 nM in a ce... Cancer
T2109 SD-208 SD-208 is a selective TGF-βRI (ALK5) inhibitor with IC50 of 48 nM, >100-fold selectiv... Immunology
T2098 A 77-01 A 77-01 is a potent inhibitor of TGF-(beta) type I receptor superfamily activin-like ... Immunology
T2001 PF-573228 PF-573228 is an ATP-competitive inhibitor of FAK with IC50 of 4 nM in a cell-free ass... Other
T1996 Defactinib (VS-6063, PF-04554878) Defactinib (VS-6063, PF-04554878) is a selective, and orally active FAK inhibitor. Ph... Other
T1967 AZD-3463 AZD3463 is a novel orally bioavailable ALK inhibitor with Ki of 0.75 nM, which also i... Immunology
T1962 ASP 3026 ASP3026 is a novel and selective inhibitor for ALK with IC50 of 3.5 nM. Phase 1. Immunology
T1950 PND-1186 PND-1186 (VS-4718) is a reversible and selective FAK inhibitor with IC50 of 1.5 nM. P... Other
T1944 LDN-214117 LDN-214117 is a potent and selective ALK2 inhibitor with IC50 of 22 nM; > 100 fold se... Immunology
T1943 ML347 ML347(DN193719) is a highly selective ALK1/ALK2 inhibitor with IC50s of 46/32 nM; sho... Other
T1942 DMH-1 DMH-1 is a potent and selective BMP inhibitor with IC50s of 27/107.9/<5 nM for ALK1/2... Other
T1936 CH5424802 CH5424802(AF 802; Alectinib) is a potent ALK inhibitor with IC50 of 1.9 nM, sensitive... Other
T1935 LDN193189 LDN193189(DM 3189) is a selective BMP signaling inhibitor, inhibits the transcription... Other
T1918 NVP-TAE 226 NVP-TAE226 is a potent FAK inhibitor with IC50 of 5.5 nM and modestly potent to Pyk2(... Other
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