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Raf
Cat.No. Product Name Information Area
T4194 CID-25014542 CID-25014542 is novel inhibitor of Raf kinases. Others
T3711 RAF709 RAF709 is a novel?Raf?kinase inhibitor extracted from patent WO2014151616A1, compound... Cancer
T6971 RO5126766 (CH5126766) RO5126766 (CH5126766) is a dual RAF/MEK inhibitor with IC50 of 8.2 nM,19 nM, 56 nM, a... Others
T6895 MLN2480 MLN2480 is an oral, selective pan-Raf kinase inhibitor in chinical trials. Others
T6882 LY3009120 LY03009120 is a potent pan-Raf inhibitor with IC50 of 44 nM, 31-47 nM, and 42 nM for ... Others
T6487 Encorafenib (LGX818) LGX818 is an orally available mutated BRaf V600E inhibitor(IC50=0.3 nM) with potentia... Cancer
T6525 GW5074 GW5074 is a potent and selective c-Raf inhibitor with IC50 of 9 nM, no effect on the ... Cancer
T2624 OSI-930 OSI-930 is a potent inhibitor of Kit, KDR and CSF-1R with IC50 of 80 nM, 9 nM and 15 ... Cancer
T2473 PLX-4720 PLX4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cel... Other
T2382 Vemurafenibhot Vemurafenib (PLX4032, RG7204) is a novel and potent inhibitor of B-RafV600E with IC50... Cancer
T2295 SB-590885 SB590885 is a potent B-Raf inhibitor with Ki of 0.16 nM in a cell-free assay, 11-fold... Other
T2293 SGX-523 SGX-523 is a selective Met inhibitor with IC50 of 4 nM, no activity to BRAFV599E, c-R... Cancer
T2267 BQU57 BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft... Other
T2074 B-Raf inhibitor 1 B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor with cell IC50s of 0.31 u... Other
T2070 CEP-32496 CEP-32496 is a highly potent inhibitor of BRAF(V600E/WT) and c-Raf with Kd of 14 nM/3... Other
T1953 L-779450 L-779450 is a potent, ATP-competitive Raf kinase inhibitor (IC50 =10 nM) that display... Other
T1903 Dabrafenib (GSK2118436)hot Dabrafenib (GSK2118436) is a mutant BRAFV600 specific inhibitor with IC50 of 0.8 nM i... Cancer
T1892 Kobe2602 kobe2602 is a novel and effective small-molecule compound inhibiting Ras–Raf interact... Other
T1886 TAK632 TAK-632 is a potent pan-Raf inhibitor with IC50 of 8.3 nM and 1.4 nM for B-Raf(wt) an... Other
T1876 Kobe0065 Kobe0065 is a novel and effective small-molecule compound inhibiting Ras–Raf interact... Other
T1851 ZM 336372 ZM 336372 is a potent and selective c-Raf inhibitor with IC50 of 70 nM, 10-fold selec... Other
T1845 B-Raf IN 1 B-Raf IN 1 is a highlt potent and selective B-Raf inhibitor with IC50 of 24 nM; equip... Other
T1792 Regorafenib Regorafenib (BAY 73-4506) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDG... Cancer
T0093L Sorafenib Sorafenib (rINN), marketed as Nexavar by Bayer, is a drug approved for the treatment ... Cancer
T0093 Sorafenib tosylate Sorafenib tosylate (BAY 43-9006) is a potent inhibitor of Raf-1 with IC50 values of 6... Cancer
T6320 GDC-0879 GDC-0879 is a novel, potent, and selective B-Raf inhibitor with IC50 of 0.13 nM with ... Cancer
T6318 AZ 628 AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM... Cancer
T6296 RAF265 RAF265 (CHIR-265) is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC5... Cancer
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