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mTOR
Cat.No. Product Name Information Area
T3514 CZ415 CZ415 is a potent and highly selective mTOR inhibitor Others
T3692 GNE 477 GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor with IC50 of 4 nM for PI... Others
T3351 CC-223 CC-223 is an orally available inhibitor of the mammalian target of rapamycin (mTOR) w... Cancer
T3656 PKI-402 PKI-402 is a potent dual pan-PI3K/mTOR inhibitor targeting PI3Kα/β/γ/δ and mTOR with ... Others
T3153 MLN1117 MLN1117 (INK1117) is a p110 inhibitor which inhibits p110α, p110β, p110γ, p110δ with ... Cancer
T3395 Timosaponin AIIInew Timosaponin AIII induces autophagy in HeLa cells followed by apoptotic cell death (IC... Others
T6510 GDC-0349 GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 n... Cancer
T6732 WYE-687 WYE-687 is an ATP-competitive and selective inhibitor of mTOR with IC50 of 7 nM; bloc... Cancer
T6730 WAY-600 WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 n... Cancer
T6731 WYE-354 WYE-354 is a potent, specific and ATP-competitive inhibitor of mTOR with IC50 of 5 nM... Cancer
T6100 Torin 2 Torin 2 is a potent and selective mTOR inhibitor with IC50 of 0.25 nM; 800-fold great... Cancer
T6045 Torin 1 Torin 1 is a potent inhibitor of mTORC1/2 with IC50 of 2 nM/10 nM; exhibits 1000-fold... Cancer
T6033 Zotarolimus(ABT-578) Zotarolimus (ABT-578) is an analogue of rapamycin, and inhibits FKBP-12 binding with ... Cancer
T6030 XL388 XL388 is a highly potent, selective, ATP-competitive inhibitor of mTOR with IC50 of ... Cancer
T2995 Chrysophanic Acid Extracted from Rheum palmatum L.;Suitability:Boiling ethanol,benzene,chloroform,ether... Cancer
T2706 Palomid 529 Palomid 529 (P529) inhibits both the mTORC1 and mTORC2 complexes, reduces phosphoryla... Cancer
T2619 CH5132799 CH5132799 inhibits class I PI3Ks, particularly PI3Kα with IC50 of 14 nM; less potent ... Cancer
T2475 KU-0063794 KU-0063794 is a potent and highly specific dual-mTOR inhibitor of mTORC1 and mTORC2 w... Other
T2434 LY 303511 LY303511, an inactive analogue of LY294002, is a mTOR inhibitor that did not inhibit ... Other
T2415 PP121 PP-121 is a multi-targeted inhibitor of PDGFR, Hck, mTOR, VEGFR2, Src and Abl with IC... Cancer
T2414 PP 242 Torkinib (PP242) is a selective mTOR inhibitor with IC50 of 8 nM in cell-free assays;... Other
T2357 GSK1059615 GSK1059615 is a dual inhibitor of PI3Kα/β/δ/γ (reversible) and mTOR with IC50 of 0.4 ... Cancer
T2235 BEZ235hot BEZ235 (NVP-BEZ235, Dactolisib) is a dual ATP-competitive PI3K and mTOR inhibitor for... Cancer
T2145 Temsirolimus Temsirolimus is an intravenous drug for the treatment of renal cell carcinoma (RCC), ... Immunology
T2144 Tacrolimus Tacrolimus is a macrolide isolated from the culture broth of a strain of Streptomyces... Immunology
T2084 ETP-46464 ETP-46464 is a potent and selective inhibitor of ATR with IC50 of 25 nM. Other
T1970 PKI-587 Gedatolisib (PF-05212384, PKI-587) is a highly potent dual inhibitor of PI3Kα, PI3Kγ ... Other
T1961 AZD2014 AZD2014 is a novel mTOR inhibitor with IC50 of 2.8 nM in a cell-free assay; highly se... Other
T1958 AZ20 AZ20 is a novel potent and selective inhibitor of ATR kinase with IC50 of 5 nM in a c... Other
T1908 MHY1485 MHY1485 is a mTOR activator; inhibits the autophagic process by inhibition of fusion ... Other
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