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Rocilinostat (ACY-1215)  
Catalog No. T2489    CAS 1316214-52-4
Pack Size
Availability
Price/USD
Quantity
5mg
In stock
43.00
10mg
In stock
60.00
25mg
In stock
72.00
50mg
In stock
102.00
100mg
In stock
179.00
1g
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0.00
5g
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0.00
10mM * 1mL (in DMSO)
In stock
47.00
Bulk Size: Please Quote for Discount
Documents and Quality Management
Purity:99.21% COA Datasheet HNMR HPLC MSDS
Biological Activity:

Product Description:

Rocilinostat (ACY-1215) is a selective HDAC6 inhibitor with IC50 of 5 nM in a cell-free assay. It is >10-fold more selective for HDAC6 than HDAC1/2/3 (class I HDACs) with slight activity against HDAC8, minimal activity against HDAC4/5/7/9/11, Sirtuin1, and Sirtuin2. Phase 2.

Target:
HDAC6; HDAC3; HDAC2; HDAC1;
Research Area:
Cancer
Chemical Information:
Molecular Weight 433.5
Formula C24H27N5O3
CAS Number 1316214-52-4
Solubility DMSO: 86mg/ml(198.39 mM);Water: <1mg/ml;Ethanol: <1mg/ml
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

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Reference

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