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ACY-241  
Catalog No. T3661    CAS 1316215-12-9
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Availability
Price/USD
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5mg
In stock
119.00
10mg
In stock
187.00
25mg
In stock
373.00
50mg
In stock
689.00
1g
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0.00
5g
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0.00
10mM * 1mL (in DMSO)
In stock
131.00
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Documents and Quality Management
Purity:98.00% COA Datasheet
Biological Activity:

Product Description:

ACY-241, also known as Citarinostat, is a potent, selective and orally available histone deacetylase (HDAC) inhibitor, with potential antineoplastic activity. Upon oral administration, ACY-241 inhibits the activity of HDACs; this results in an accumulation of highly acetylated chromatin histones, the induction of chromatin remodeling and an altered pattern of gene expression. This leads to the inhibition of tumor oncogene transcription, and the selective transcription of tumor suppressor genes, which inhibit tumor cell division and induce tumor cell apoptosis.

Target:
HDAC;
Research Area:
Cancer
Chemical Information:
Molecular Weight 467.95
Formula C24H26ClN5O3
CAS Number 1316215-12-9
Solubility
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Related Compound Libraries
This product is contained In the following compound libraries:
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Reference

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