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Home > Membrane transporter/Ion Channel > TRP/TRPV > AMG-517
Catalog No. T6379    CAS 659730-32-2
Pack Size
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10mM * 1mL (in DMSO)
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In Stock
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Documents and Quality Management
Purity:99.08% COA Datasheet HPLC
Biological Activity:

Product Description:

AMG 517 is a potent and selective TRPV1 antagonist, antagonizes capsaicin, proton, and heat activation of TRPV1 with IC50 of 0.76 nM, 0.62 nM and 1.3 nM.

Research Area:
Nervous system
Chemical Information:
Molecular Weight 430.4
Formula C20H13F3N4O2S
CAS Number 659730-32-2
Solubility DMSO: 86mg/ml(199.81 mM);Water: <1mg/ml;Ethanol: <1mg/ml
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Related Compound Libraries
This product is contained In the following compound libraries:
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