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BIBF 1120  
Catalog No. T1777    CAS 656247-17-5
Pack Size
Availability
Price/USD
Quantity
10mg
In Stock
54.00
50mg
In Stock
94.00
10mM * 1mL (in DMSO)
In Stock
58.00
25mg
In Stock
75.00
Bulk Size: Please Quote for Discount
Documents and Quality Management
Purity:99.65% COA Datasheet HNMR HPLC
Biological Activity:

Product Description:

Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM in cell-free assays. Phase 3.

Target:
VEGFR; PDGFR; FGFR;
Research Area:
Other
Chemical Information:
Molecular Weight 539.62
Formula C31H33N5O4
CAS Number 656247-17-5
Solubility Ethanol: 3 mg/mL (5.55 mM); DMSO: 6 mg/mL (11.11 mM)
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

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Reference

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