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Home > Chromatin/Epigenetic > JAK > Baricitinib
Baricitinib  
Catalog No. T2485    CAS 1187594-09-7
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2mg
In stock
27.00
5mg
In stock
51.00
10mg
In stock
60.00
25mg
In stock
83.00
50mg
In stock
102.00
100mg
In stock
128.00
200mg
In stock
204.00
500mg
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374.00
1g
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0.00
5g
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0.00
10mM * 1mL (in DMSO)
In stock
56.00
Bulk Size: Please Quote for Discount
Documents and Quality Management
Purity:99.50% COA Datasheet HNMR HPLC MSDS
Biological Activity:

Product Description:

Baricitinib (LY3009104, INCB028050) is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM in cell-free assays, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2. Phase 3.

Target:
TYK2; JAK3; JAK2; JAK1; c-Met; Chk2;
Research Area:
Cancer
Chemical Information:
Molecular Weight 371.42
Formula C16H17N7O2S
CAS Number 1187594-09-7
Solubility DMSO: 74mg/ml(199.24 mM);Water: <1mg/ml;Ethanol: <1mg/ml
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

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Reference

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