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Cediranib  
Catalog No. T2500    CAS 288383-20-0
Pack Size
Availability
Price/USD
Quantity
10mg
In Stock
71.00
50mg
In Stock
218.00
10mM * 1mL (in DMSO)
In Stock
57.00
25mg
In Stock
128.00
Bulk Size: Please Quote for Discount
Documents and Quality Management
Purity:99.94% COA Datasheet HNMR HPLC MSDS
Biological Activity:

Product Description:

Cediranib (AZD2171) is a highly potent VEGFR(KDR) inhibitor with IC50 of <1 nM, also inhibits Flt1/4 with IC50 of 5 nM/≤3 nM, similar activity against c-Kit and PDGFRβ, 36-, 110-fold and >1000-fold selective more for VEGFR than PDGFR-α, CSF-1R and Flt3 in HUVEC cells. Phase 3.

Target:
PDGFRβ; VEGFR1/FLT1; VEGFR2/KDR; c-Kit; VEGFR3/FLT4;
Research Area:
Cancer
Chemical Information:
Molecular Weight 450.51
Formula C25H27FN4O3
CAS Number 288383-20-0
Solubility DMSO: 90 mg/mL (199.77 mM)
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

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Reference

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