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Home > Tyrosine Kinase/Adaptors > PDGFR > Crenolanib
Crenolanib  
Catalog No. T2677    CAS 670220-88-9
Pack Size
Availability
Price/USD
Quantity
2mg
In Stock
70.00
10mg
In Stock
138.00
50mg
In Stock
378.00
100mg
In Stock
618.00
10mM * 1mL (in DMSO)
In Stock
115.00
5mg
In Stock
102.00
Bulk Size: Please Quote for Discount
Documents and Quality Management
Purity:99.36% COA Datasheet HNMR HPLC MSDS
Biological Activity:

Product Description:

Crenolanib (CP-868596) is a potent and selective inhibitor of PDGFRα/β with Kd of 2.1 nM/3.2 nM in CHO cells, also potently inhibits FLT3, sensitive to D842V mutation not V561D mutation, >100-fold more selective for PDGFR than c-Kit, VEGFR-2, TIE-2, FGFR-2, EGFR, erbB2, and Src.

Target:
PDGFRβ; PDGFRα;
Research Area:
Cancer
Chemical Information:
Molecular Weight 443.54
Formula C26H29N5O2
CAS Number 670220-88-9
Solubility Ethanol: 7 mg/mL (15.78 mM); DMSO: 89 mg/mL warmed (200.65 mM)
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

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Reference

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