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Home > Tyrosine Kinase/Adaptors > CSF/1R > Linifanib
Linifanib  
Catalog No. T2514    CAS 796967-16-3
Pack Size
Availability
Price/USD
Quantity
10mg
In Stock
75.00
50mg
In Stock
192.00
10mM * 1mL (in DMSO)
In Stock
57.00
25mg
In Stock
142.00
Bulk Size: Please Quote for Discount
Documents and Quality Management
Purity:99.97% COA Datasheet HNMR HPLC MSDS
Biological Activity:

Product Description:

Linifanib (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR, CSF-1R, Flt-1/3 and PDGFRβ with IC50 of 4 nM, 3 nM, 3 nM/4 nM and 66 nM respectively, mostly effective in mutant kinase-dependent cancer cells (i.e. FLT3). Phase 3.

Target:
VEGFR3/FLT4; Kit; PDGFRβ; FLT3; CSF-1R; VEGFR2/KDR; VEGFR1/FLT1;
Research Area:
Cancer
Chemical Information:
Molecular Weight 375.4
Formula C21H18FN5O
CAS Number 796967-16-3
Solubility DMSO: 75 mg/mL (199.78 mM)
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

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Reference

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