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Mollugin  
Catalog No. T3673    CAS 55481-88-4
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10mg
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43.00
25mg
In stock
68.00
50mg
In stock
112.00
100mg
In stock
190.00
1g
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0.00
5g
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0.00
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Documents and Quality Management
Purity:98.00% COA Datasheet HNMR
Biological Activity:

Product Description:

Mollugin may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upregulation of the HO-1 and Nrf2 pathways and the downregulation of NF- κ B. Mollugin may be a novel therapeutic candidate for bone loss-associated disorders including osteoporosis, rheumatoid arthritis, and periodontitis. Also, it has anticancer efficacy, can modulate the HER2 pathway in HER2-overexpressing cancer cells with a potential role in the treatment and prevention of human breast and ovarian cancer with HER2 overexpression.

Target:
HER2;
Research Area:
Others
Chemical Information:
Molecular Weight 284.3
Formula C17H16O4
CAS Number 55481-88-4
Solubility Chloroform, Dichloromethane, Ethyl Acetate,Acetone: Soluble
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Related Compound Libraries
This product is contained In the following compound libraries:
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Reference

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