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Home > Tyrosine Kinase/Adaptors > RET > Motesanib Diphosphate (AMG-706)
Motesanib Diphosphate (AMG-706)  
Catalog No. T2288L    CAS 857876-30-3
Pack Size
Availability
Price/USD
Quantity
5mg
In Stock
35.00
25mg
In Stock
108.00
50mg
In Stock
152.00
100mg
In Stock
268.00
10mM * 1mL (in DMSO)
In Stock
40.00
10mg
In Stock
48.00
Bulk Size: Please Quote for Discount
Documents and Quality Management
Purity:99.33% COA Datasheet HNMR HPLC MSDS
Biological Activity:

Product Description:

Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively; similar activity against Kit, ~10-fold more selective for VEGFR than PDGFR and Ret. Phase 3.

Target:
PDGFR; RET; Kit; VEGFR3; Flk1; VEGFR2 ; VEGFR1;
Research Area:
Cancer
Chemical Information:
Molecular Weight 569.44
Formula C22H23N52H3PO4
CAS Number 857876-30-3
Solubility DMSO: 100mg/ml(175.61 mM);Water: 19mg/ml(33.37 mM);Ethanol: <1mg/ml
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

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Reference

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