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Motesanib  
Catalog No. T2288    CAS 453562-69-1
Pack Size
Availability
Price/USD
Quantity
1mg
In Stock
24.00
10mg
In Stock
48.00
25mg
In Stock
98.00
50mg
In Stock
152.00
10mM * 1mL (in DMSO)
In Stock
48.00
5mg
In Stock
35.00
Bulk Size: Please Quote for Discount
Documents and Quality Management
Purity:99.00% COA Datasheet HNMR
Biological Activity:

Product Description:

Motesanib is an orally bioavailable receptor tyrosine kinase inhibitor with potential antineoplastic activity. AMG 706 selectively targets and inhibits vascular endothelial growth factor (VEGFR), platelet-derived growth factor (PDGFR), Kit, and Ret receptors, thereby inhibiting angiogenesis and cellular proliferation.

Target:
PDGFR; RET; Kit; VEGFR3; Flk1; VEGFR2 ; VEGFR1;
Research Area:
Cancer
Chemical Information:
Molecular Weight 373.45
Formula C22H23N5O
CAS Number 453562-69-1
Solubility DMSO: ≥ 30 mg/mL
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

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Reference

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