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Home > Chromatin/Epigenetic > JAK > Pyridone 6
Pyridone 6  
Catalog No. T3080    CAS 457081-03-7
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2mg
In stock
102.00
5mg
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167.00
10mg
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230.00
25mg
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383.00
50mg
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670.00
100mg
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1190.00
1g
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0.00
5g
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0.00
10mM * 1mL (in DMSO)
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173.00
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Documents and Quality Management
Purity:98.74% COA Datasheet HNMR HPLC MSDS
Biological Activity:

Product Description:

Pyridone 6(CMP 6) is a potent and selective inhibitor of JAK1 (IC50=15 nM, murine JAK1), JAK2 (IC50=1 nM), JAK3 (Ki=5 nM), and Tyk2 (IC50=1 nM); displaying significantly weaker affinities (130 nM to 10 mM) for other protein tyrosine kinases.

Target:
Try2; JAK3; JAK2; JAK1;
Research Area:
Cancer
Chemical Information:
Molecular Weight 309.34
Formula C18H16FN3O
CAS Number 457081-03-7
Solubility DMSO: > 5mg/ml
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Related Compound Libraries
This product is contained In the following compound libraries:
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Reference

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