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Home > Chromatin/Epigenetic > Pim > SGI-1776 free base
SGI-1776 free base  
Catalog No. T3078    CAS 1025065-69-3
Pack Size
Availability
Price/USD
Quantity
2mg
9 days
53.00
10mg
9 days
158.00
25mg
9 days
266.00
50mg
9 days
409.00
10mM * 1mL (in DMSO)
9 days
88.00
5mg
9 days
76.00
Bulk Size: Please Quote for Discount
Documents and Quality Management
Purity:99.50% COA Datasheet HNMR HPLC MSDS
Biological Activity:

Product Description:

SGI-1776 free base is a novel ATP competitive inhibitor of Pim1 with IC50 of 7 nM in a cell-free assay, 50- and 10-fold selective versus Pim2 and Pim3, also potent to Flt3 and haspin. Phase 1.

Target:
Pim3; Pim2; Pim1; FLT3;
Research Area:
Cancer
Chemical Information:
Molecular Weight 405.42
Formula C20H22F3N5O
CAS Number 1025065-69-3
Solubility Ethanol: 81 mg/mL (199.79 mM); DMSO: 81 mg/mL (199.79 mM)
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

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Reference

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