info@targetmol.com    Tel: (857) 239-0968 / (617) 419-7131
Home > Chromatin/Epigenetic > c/Kit > XL019
XL019  
Catalog No. T3072    CAS 945755-56-6
Pack Size
Availability
Price/USD
Quantity
2mg
In Stock
53.00
10mg
In Stock
136.00
25mg
In Stock
220.00
50mg
In Stock
427.00
100mg
In Stock
718.00
10mM * 1mL (in DMSO)
In Stock
88.00
5mg
In Stock
76.00
Bulk Size: Please Quote for Discount
Documents and Quality Management
Purity:99.23% COA Datasheet HNMR HPLC MSDS
Biological Activity:

Product Description:

XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, exhibiting >50-fold selectivity over JAK1, JAK3 and TYK2. Phase 1.

Target:
c-Kit; FLT3; JAK1; PDGFRβ; JAK2;
Research Area:
Cancer
Chemical Information:
Molecular Weight 444.53
Formula C25H28N6O2
CAS Number 945755-56-6
Solubility DMSO: 16mg/ml(35.99 mM);Water: <1mg/ml;Ethanol: <1mg/ml
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Product Recommendations
  • S-Ruxolitinib (INCB018424), S-Ruxolitinib is the chirality of INCB018424, which is the first potent, selective, JAK1/2 inhibitor...
  • Cerdulatinib hydrochloride, Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 1...
  • Pacritinib (SB1518), Pacritinib (SB1518) is a potent and selective inhibitor of Janus Kinase 2 (JAK2) and Fms-Like Tyrosi...
  • Pyridone 6, Pyridone 6(CMP 6) is a potent and selective inhibitor of JAK1 (IC50=15 nM, murine JAK1), JAK2 (IC50=...
  • GLPG0634 analogue, GLPG0634 analogue is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JA...

 

Reference

If you have additional questions, Please send us a message. * Required