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Home > Tyrosine Kinase/Adaptors > Raf > Regorafenib
Regorafenib  
Catalog No. T1792    CAS 755037-03-7
Pack Size
Availability
Price/USD
Quantity
5mg
In Stock
36.00
25mg
In Stock
69.00
50mg
In Stock
96.00
100mg
In Stock
142.00
10mM * 1mL (in DMSO)
In Stock
55.00
10mg
In Stock
54.00
Bulk Size: Please Quote for Discount
Documents and Quality Management
Purity:99.00% COA Datasheet HNMR HPLC MSDS
Biological Activity:

Product Description:

Regorafenib (BAY 73-4506) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM in cell-free assays, respectively.

Target:
VEGFR3; VEGFR2; VEGFR1; Raf-1; B-Raf;
Research Area:
Cancer
Chemical Information:
Molecular Weight 482.82
Formula C21H15ClF4N4O3
CAS Number 755037-03-7
Solubility DMSO: 97 mg/mL (200.9 mM)
Storage 3 years -20°C powder;
2 years -80°C in solvent;
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

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Reference

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