AN-2690
ID:T3349Hot Degree:
Size Price(USD) Stock Qty Select
5mg 44.00 9 days
10mg 68.00 9 days
25mg 135.00 9 days
50mg 222.00 9 days
100mg 406.00 9 days
10mM * 1mL (in DMSO) 46.00 9 days

Quality management and product safety instructions
Related compound libraries
This product contains In the following compound libraries:
Product Information

HEREBY WE DECLARE TAHT ALL DATA ARE DEREIVED FROM PUBLIC RESOURCES, TARGETMOL IS NOT RESPONSIBLE FOR THEIR EFFECTIVENESS.

Biological Activity Figure

Pathway
Biological Activity:

Product Description

AN-2690(Tavaborole), an antifungal agent with activity against Trichophyton species, in a topical solution formulation, for the potential treatment of onychomycosis.

Target

Antifungle View more

IC50 Value

Diseases and Conditions

Immunology
In vitro
In vivo
Chemical Information:

Molecular Weight

151.93

Storage

3years    -20 ℃    powder

2years    -80 ℃    In solvent

Formula

C7H6BFO2

CAS:

174671-46-6

Remark

For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Solubility

In vitro

Ethanol

DMSO

Soluble

Water

In vivo

* <1 mg/ml refers to the product slightly soluble or insoluble
Preparing Stock Solutions
Concentration Volume(DMSO) Mass
1mg 5mg 10mg
1mM 6.582mL 32.9099mL 65.8198mL
5mM 1.3164mL 6.582mL 32.9099mL
10mM 0.0658mL 3.291mL 6.582mL
50mM 0.0132mL 0.6582mL 3.291mL
Reference
Clinical Data( Data from the:http:// clinicaltrials.gov)
Conversion of different model animals based on BSA(Value based on data from FDA Draft Guidelines)
Animal A (mg/kg)=Animal B(mg/kg)multiplied by

AnimalBm coefficient

 

AnimalAm coefficient

 

For example, to modify the dose of resveratrol uesd for a mouse(22.4mg/kg) to a dose based on the BSA for a rat, multiply 22.4mg/kg by the Km factor for a mouse and zhen divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2mg/kg

Customers who bought this product also buy
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

If you have additional questions,Please send us a message.

* Required

Products related targets
  • Carbendazim

    Carbendazim is a broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplast...

  • Fenticonazole Nitrate

    Fenticonazole Nitrate is an azole antifungal agent.

  • Anidulafungin

    Anidulafungin (LY303366), an echinocandin derivative, inhibits glucan synthase activity, used as an ...

  • Xanthone

    Xanthone is an organic compound and can be prepared by the heating of phenyl salicylate. In 1939, x...

  • Xanthoxyline

    Derivatives of xanthoxyline have antispasmodic activity.

Recently Viewed Products