Magnolol
ID:T3000Hot Degree:
Size Price(USD) Stock Qty Select
10mg 20.00 In Stock
25mg 40.00 In Stock
50mg 75.00 In Stock
250mg 198.00 In Stock
10mM * 1mL (in DMSO) 37.00 In Stock

Quality management and product safety instructions
Related compound libraries
This product contains In the following compound libraries:
Product Information

HEREBY WE DECLARE TAHT ALL DATA ARE DEREIVED FROM PUBLIC RESOURCES, TARGETMOL IS NOT RESPONSIBLE FOR THEIR EFFECTIVENESS.

Biological Activity Figure

Pathway
Biological Activity:

Product Description

Magnolol is isomeric to honokiol (sc-202653). Magnolol is an anxiolytic,anti-thrombotic and antibacterial. . Inhibitor of nitric oxide (NO) and TNF-α production in LPS-activated macrophages by the suppression of inducible nitric oxide synthase(iNOS; NOS

Target

NF-κB p53 PPARγ View more

IC50 Value

Diseases and Conditions

Immunology
In vitro
In vivo
Chemical Information:

Molecular Weight

266.32

Storage

3years    -20 ℃    powder

2years    -80 ℃    In solvent

Formula

C18H18O2

CAS:

528-43-8

Remark

For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Solubility

In vitro

Ethanol

53 mg/mL (199.0 mM)

DMSO

53 mg/mL (199.0 mM)

Water

In vivo

* <1 mg/ml refers to the product slightly soluble or insoluble
Preparing Stock Solutions
Concentration Volume(DMSO) Mass
1mg 5mg 10mg
1mM 3.7549mL 18.7744mL 37.5488mL
5mM 0.751mL 3.7549mL 18.7744mL
10mM 0.0375mL 1.8774mL 3.7549mL
50mM 0.0075mL 0.3755mL 1.8774mL
Reference
Clinical Data( Data from the:http:// clinicaltrials.gov)
Conversion of different model animals based on BSA(Value based on data from FDA Draft Guidelines)
Animal A (mg/kg)=Animal B(mg/kg)multiplied by

AnimalBm coefficient

 

AnimalAm coefficient

 

For example, to modify the dose of resveratrol uesd for a mouse(22.4mg/kg) to a dose based on the BSA for a rat, multiply 22.4mg/kg by the Km factor for a mouse and zhen divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2mg/kg

Customers who bought this product also buy
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

If you have additional questions,Please send us a message.

* Required

Products related targets
  • Palmitoylethanolamide

    Palmitoylethanolamide(PEA) is an endogenous fatty acid amide and selectively activates PPAR-α in vit...

  • AZ6102

    AZ6102 is a potent TNKS1/2 inhibitor that has 100-fold selectivity against other PARP family enzymes...

  • GW0742

    GW0742 is a potent and highly selective PPARβ/δ agonist, with IC50 of 1 nM, with 1000-fold selectivi...

  • Rosiglitazone hydrochloride

    Rosiglitazone HCl is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the...

  • T0070907

    T0070907 is a potent and selective PPARγ inhibitor with IC50 of 1 nM, with a >800-fold selectivity o...

Recently Viewed Products