Pomalidomide
ID:T2384Hot Degree:
Size Price(USD) Stock Qty Select
10mg 67.00 In Stock
50mg 201.00 In Stock
100mg 333.00 In Stock
10mM * 1mL (in DMSO) 57.00 In Stock

Quality management and product safety instructions
Related compound libraries
This product contains In the following compound libraries:
Product Information

HEREBY WE DECLARE TAHT ALL DATA ARE DEREIVED FROM PUBLIC RESOURCES, TARGETMOL IS NOT RESPONSIBLE FOR THEIR EFFECTIVENESS.

Biological Activity Figure

Pathway
Biological Activity:

Product Description

Pomalidomide inhibits LPS-induced TNF-α release with IC50 of 13 nM in PBMCs.

Target

TNF-α View more

IC50 Value

13nM

Diseases and Conditions

Cancer
In vitro
In vivo
Chemical Information:

Molecular Weight

273.24

Storage

3years    -20 ℃    powder

2years    -80 ℃    In solvent

Formula

C13H11N3O4

CAS:

19171-19-8

Remark

For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Solubility

In vitro

DMSO

55 mg/mL (201.28 mM)

Water

In vivo

1% DMSO+30% polyethylene glycol+1% Tween 80

15 mg/mL

* <1 mg/ml refers to the product slightly soluble or insoluble
Preparing Stock Solutions
Concentration Volume(DMSO) Mass
1mg 5mg 10mg
1mM 3.6598mL 18.2989mL 36.5979mL
5mM 0.732mL 3.6598mL 18.2989mL
10mM 0.0366mL 1.8299mL 3.6598mL
50mM 0.0073mL 0.366mL 1.8299mL
Reference
Clinical Data( Data from the:http:// clinicaltrials.gov)
Conversion of different model animals based on BSA(Value based on data from FDA Draft Guidelines)
Animal A (mg/kg)=Animal B(mg/kg)multiplied by

AnimalBm coefficient

 

AnimalAm coefficient

 

For example, to modify the dose of resveratrol uesd for a mouse(22.4mg/kg) to a dose based on the BSA for a rat, multiply 22.4mg/kg by the Km factor for a mouse and zhen divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2mg/kg

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Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

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