Secoisolariciresinol diglucoside
ID:T3415Hot Degree:
Size Price(USD) Stock Qty Select
10mg 50.00 In Stock
25mg 83.00 In Stock
50mg 133.00 In Stock
100mg 222.00 In Stock

Quality management and product safety instructions
Related compound libraries
This product contains In the following compound libraries:
Product Information

HEREBY WE DECLARE TAHT ALL DATA ARE DEREIVED FROM PUBLIC RESOURCES, TARGETMOL IS NOT RESPONSIBLE FOR THEIR EFFECTIVENESS.

Biological Activity Figure

Pathway
Biological Activity:

Product Description

Secoisolariciresinol Diglucoside was cytoprotective in an in vitro model of iron overload induced redox-inflammatory damage.? Synthetic Secoisolariciresinol Diglucoside at 25 mg/kg b.w., exerts anti hyperglycemic effect by preventing the liver from peroxidation damage through inhibition of ROS level mediated increased level of enzymatic and non-enzymatic antioxidants.]

Target

ROS View more

IC50 Value

Diseases and Conditions

Cardiovascular system
In vitro
In vivo
Chemical Information:

Molecular Weight

686.71

Storage

3years    -20 ℃    powder

2years    -80 ℃    In solvent

Formula

C32H46O16

CAS:

148244-82-0

Remark

For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Solubility

In vitro

Pyridine, Methanol, Ethanol

DMSO

Water

In vivo

* <1 mg/ml refers to the product slightly soluble or insoluble
Preparing Stock Solutions
Concentration Volume(DMSO) Mass
1mg 5mg 10mg
1mM 1.4562mL 7.2811mL 14.5622mL
5mM 0.2912mL 1.4562mL 7.2811mL
10mM 0.0146mL 0.7281mL 1.4562mL
50mM 0.0029mL 0.1456mL 0.7281mL
Reference
Clinical Data( Data from the:http:// clinicaltrials.gov)
Conversion of different model animals based on BSA(Value based on data from FDA Draft Guidelines)
Animal A (mg/kg)=Animal B(mg/kg)multiplied by

AnimalBm coefficient

 

AnimalAm coefficient

 

For example, to modify the dose of resveratrol uesd for a mouse(22.4mg/kg) to a dose based on the BSA for a rat, multiply 22.4mg/kg by the Km factor for a mouse and zhen divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2mg/kg

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Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

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