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Home > Screening Libraries > Protease Inhibitor Library

Protease Inhibitor Library

Catalog No. L1100

Protease inhibitorsaremoleculesthat inhibit the function ofproteases(enzymesthat aidthe breakdown of proteins), including proteins protease inhibitors, natural protease inhibitors, and synthetic protease inhibitors. (1). Antiprotozoal activity: protease inhibitors could be used against malaria and gastrointestinal protozoal infections; (2). Antiretrovirals: protease inhibitors were the second class of antiretroviral drugs developed widely used to treat HIV/AIDS and hepatitis C; (3). Anticancer activity: Researchers are investigating whether protease inhibitors could possibly be used to treat cancer. For example, nelfinavir and atazanavir are able to kill tumor cells in culture. Inhibitors of theproteasome, such asbortezomibare now front-line drugs for the treatment ofmultiple myeloma. Marimastat and batimastatare two of thematrix metalloproteinase inhibitorsthat can be used to treat cancer.

The Protease Inhibitor Library by TargetMol, containing 162 small protease and proteasome inhibitors, can be used for research in Chemical Genomics and drug screening.

Pack Size Price
100 μL * 10 mM (in DMSO) USD 3531.00
250 μL * 10 mM (in DMSO) USD 5825.00
1 mg USD 5825.00

Product Description

  • A unique collection of 162 protease and proteasome inhibitors for research in chemical genomics, and drug screening;
  • Targets include proteasome, DPP-4, Serine protease, cysteine protease, MMP, Aspartic proteinases, etc;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

The compound library can be highly customized. You can select compounds, quantities, format (dry/solid or DMSO), plate map, and concentration to meet your specific requirement. Please check our Compound Library Instructions for more information.

Packaging and Storage

  • Powder or pre-dissolved DMSO solutions in 96 well plate with optional 2D barcode
  • Shipped with blue ice; Stable for One year as powder, 6 months at - 20 ° C in DMSO or 12months at -80 ° C in DMSO

Library Composition

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