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Serotonin Compound Library

Catalog No. L2800

Serotoninor5-hydroxytryptamine(5-HT) is amonoamine neurotransmitter, derivative from the amino acidtryptophan, and mainly located in the enterochromaffin cells in the GI tract and central nervous system (CNS). It has a popular image as a contributor to feelings of well-being andhappiness, though its actual biological function is complex and multifaceted, modulating cognition, reward, learning, memory, and numerous physiological processes. Serotonin receptors, are a group ofG protein-coupled receptorandligand-gated ion channelsfound in thecentralandperipheral nervous systems. They can be divided into 7 families ofG protein-coupled receptorsexcept for the5-HT3receptor, aligand-gated ion channel, which activate anintracellularsecond messengercascade to produce an excitatory or inhibitory response. They mediate bothexcitatory and inhibitoryneurotransmission, influencing various biological and neurological processes. The serotonin receptors are the target of a variety of pharmaceutical and recreational drugs, including manyantidepressants,antipsychotics,anorectics,antiemetics,gastroprokinetic agents,antimigraine agents,hallucinogens, andentactogens.

The Serotonin (5-HT) Compound Library by TargetMol, collecting 134 small chemicals targeting serotonin receptors, can be used for high throughput screening and high content screening, and drug discovery in neurological disorders.

Pack Size Price
100 μL * 10 mM (in DMSO) USD 2158.00
250 μL * 10 mM (in DMSO) USD 3600.00
1 mg USD 3600.00

Product Description

  • A unique collection of 134 compounds targeting serotonin receptors for high throughput screening and high content screening;
  • Targets include serotonin receptors: 5-HT1, 5-HT2, 5-HT3, 5-HT4, 5-HT6, 5-HT7, etc;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

The compound library can be highly customized. You can select compounds, quantities, format (dry/solid or DMSO), plate map, and concentration to meet your specific requirement. Please check our Compound Library Instructions for more information.

Packaging and Storage

  • Powder or pre-dissolved DMSO solutions in 96 well plate with optional 2D barcode
  • Shipped with blue ice; Stable for One year as powder, 6 months at - 20 ° C in DMSO or 12months at -80 ° C in DMSO

Library Composition

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