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Home > Screening Libraries > Nuclear-receptor Inhibitors Library

Nuclear-receptor Inhibitors Library

Catalog No. L1510

Nuclear receptors are a class of proteins, different from membrane receptors located in the cell membrane, found within cells that are responsible for sensing steroid and thyroid hormones and certain other molecules. Nuclear receptors have the ability to directly bind to DNA and regulate the expression of adjacent genes, hence these receptors are classified as transcription factors, thereby controlling the development, homeostasis, and metabolism of the organism. Over the last 15 years a growing number of nuclear receptors have been identified that coordinate genetic networks regulating lipid metabolism and energy utilization and underlie the pathogenesis of metabolic diseases, such as obesity, type II diabetes, hypertension, and cardiovascular disease.

TargetMol collects 239 reported compounds targeting nuclear receptors as Nuclear Receptor Compound Library, which can be used for research in nuclear receptor signaling and related diseases, and high throughput and high content screening for drug discovery.

Pack Size Price
100 μL * 10 mM (in DMSO) USD 2900.00
250 μL * 10 mM (in DMSO) USD 5100.00
1 mg USD 5100.00

Product Description

  • A unique collection of 239 nuclear receptor signaling targeted compounds for high throughput and high content screening;
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

The compound library can be highly customized. You can select compounds, quantities, format (dry/solid or DMSO), plate map, and concentration to meet your specific requirement. Please check our Compound Library Instructions for more information.

Packaging and Storage

  • Powder or pre-dissolved DMSO solutions in 96 well plate with optional 2D barcode
  • Shipped with dry ice.

Library Composition

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