A histone modification is a covalent post-translational enzymatic modification to histone proteins which includes methylation, phosphorylation, acetylation, ubiquitylation, and sumoylation. Histone modification impacts gene expression by altering chromatin structure or recruiting histone modifiers. Therefore, histone modifications act in diverse biological processes such as transcriptional activation/inactivation, chromosome packaging, and DNA damage/repair. Thus, quantitative detection of various histone modifications would provide useful information for a better understanding of epigenetic regulation of cellular processes and the development of histone modifying enzyme-targeted drugs.
The TargetMol’s Histone Modification Research Compound Library, a unique collection of 152 histone modification related compounds, can be used for research in histone modification and related drug screening.
|100 μL * 10 mM (in DMSO)||USD 2432.00|
|250 μL * 10 mM (in DMSO)||USD 4408.00|
|1 mg||USD 4408.00|
The compound library can be highly customized. You can select compounds, quantities, format (dry/solid or DMSO), plate map, and concentration to meet your specific requirement. Please check our Compound Library Instructions for more information.