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Cell cycle related Compound Library

Catalog No. L8100

Cell cycle, the ordered sequence of events that occur in a cell in preparation for cell division, is also divided into two periods: interphase and the mitotic (M) phase. Interphase itself is split into different phases: G1 phase, S phase and G2 phase. Cell Cycle related compounds rely on differing mechanisms of action to regulate the normal progression of the cell cycle. Some of these compounds interfere with CDK/cyclin complexes leaving cells stuck at the G2/M phase border, while others affect CaMKII phosphorylation, inducing arrest at the G1 phase. Other mechanisms of action include interference with RNA function and inhibition of protein synthesis. Many of these compounds ultimately induce apoptosis as a result of their interruption of the cell cycle. This library can be used for anti-cancer drug screening.

The TargetMol’s Cell Cycle Compound Library, a unique collection of 130 cell cycle related compounds, can be used for research in cell cycle and related drug screening.

Pack Size Price
100 μL * 10 mM (in DMSO) USD 1950.00
250 μL * 10 mM (in DMSO) USD 3380.00
1 mg USD 3380.00

Product Description

  • A unique collection of 130 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Targets include CDK, ROCK, Aurora Kinase, ATM/ATR, DNA-PK, DNA/RNA Synthesis, etc.;
  • Effective tool for research in cell cycle and related diseases, such as cancer, cardiovascular diseases, inflammation, neurodegenerative diseases, etc.;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC/LCMS validated to ensure high purity and quality;

The compound library can be highly customized. You can select compounds, quantities, format (dry/solid or DMSO), plate map, and concentration to meet your specific requirement. Please check our Compound Library Instructions for more information.

Packaging and Storage

  • Powder or pre-dissolved DMSO solutions in 96 well plate with optional 2D barcode
  • Shipped with dry ice.

Library Composition

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