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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1125 | Shikonin | NSC 252844 , Isoarnebin 4 , (+)-Shikonin , Alkanna Red , C.I. 75535 , Anchusa acid | HIV Protease , PKM , TNF , NF-κB , Chloride channel |
Shikonin (Anchusa acid) is an TMEM16A chloride channel inhibitor (IC50: 6.5 μM). Shikonin is also a selective PKM2 inhibitor and can also suppress activation of the NF-κB pathway and inhibit TNF-α. Shikonin decreases exo... |