Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(E/Z)-GSK5182 (GSK5182(Z/E)) is a racemic mixture comprising (E)-GSK5182 and (Z)-GSK5182 isomers. It acts as a highly selective and orally active inverse agonist for the estrogen-related receptor γ (ERRγ), demonstrating potency with an IC50 of 79 nM. Additionally, GSK5182 is known to induce the generation of reactive oxygen species (ROS) in hepatocellular carcinoma.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 93.00 | |
5 mg | In stock | $ 228.00 | |
10 mg | In stock | $ 372.00 | |
25 mg | In stock | $ 656.00 | |
50 mg | In stock | $ 997.00 | |
100 mg | In stock | $ 1,490.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 253.00 |
Description | (E/Z)-GSK5182 (GSK5182(Z/E)) is a racemic mixture comprising (E)-GSK5182 and (Z)-GSK5182 isomers. It acts as a highly selective and orally active inverse agonist for the estrogen-related receptor γ (ERRγ), demonstrating potency with an IC50 of 79 nM. Additionally, GSK5182 is known to induce the generation of reactive oxygen species (ROS) in hepatocellular carcinoma. |
Synonyms | GSK5182(Z/E) |
Molecular Weight | 417.54 |
Formula | C27H31NO3 |
CAS No. | T7709 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 95 mg/mL (227.52 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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(E/Z)-GSK5182 T7709 Endocrinology/Hormones Immunology/Inflammation ROS Estrogen/progestogen Receptor (E/Z)GSK5182 GSK5182(Z/E) (E/Z) GSK5182 (E/Z)-GSK 5182 (E/Z)-GSK-5182 inhibitor inhibit