Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(R)-MG-132 (Z-Leu-D-leu-leu-al) is the enantiomer of MG-132. (R)-MG-132 stereoisomer is a more potent proteasome inhibitor than MG-132.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 34.00 | |
5 mg | In stock | $ 55.00 | |
10 mg | In stock | $ 76.00 | |
25 mg | In stock | $ 137.00 | |
50 mg | In stock | $ 228.00 | |
100 mg | In stock | $ 347.00 | |
500 mg | In stock | $ 838.00 | |
1 g | In stock | $ 1,160.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 70.00 |
Description | (R)-MG-132 (Z-Leu-D-leu-leu-al) is the enantiomer of MG-132. (R)-MG-132 stereoisomer is a more potent proteasome inhibitor than MG-132. |
In vitro | (R)-MG-132 is studied as a potential chymotrypsin-like inhibitor, trypsin-like, and peptidylglutamyl peptide hydrolyzing activities of proteasome. MG-132 and (R)-MG-132 are investigated for inhibition of ChTL, trypsin-like (TL) and peptidylglutamyl peptide hydrolyzing (PGPH) activities of purified 20S proteasomes isolated from human erythrocytes.For (R)-MG-132, the IC50s of 0.22 μM, 34.4 μM, and 2.95 μM for ChTL, TL, and PGPH, respectively. For MG-132, the IC50s of 0.89 μM, 104.43 μM, and 5.7 μM for ChTL, TL, and PGPH, respectively. |
Synonyms | (S,R,S)-(-)-MG-132, Z-Leu-D-leu-leu-al |
Molecular Weight | 475.62 |
Formula | C26H41N3O5 |
CAS No. | 1211877-36-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (210.25 mM)
You can also refer to dose conversion for different animals. More
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(R)-MG-132 1211877-36-9 Proteases/Proteasome Ubiquitination Proteasome MG-132 (S,R,S)-(-)-MG-132 inhibit MG132 (R)MG132 Inhibitor MG 132 Z-Leu-D-leu-leu-al (R) MG 132 inhibitor