Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 57.00 | |
5 mg | In stock | $ 139.00 | |
10 mg | In stock | $ 222.00 | |
25 mg | In stock | $ 447.00 | |
50 mg | In stock | $ 659.00 | |
100 mg | In stock | $ 939.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 179.00 |
Description | (S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor. |
Targets&IC50 | EGFR exon 20 NPH:51.2 nM (IC50), EGFR L858R/T790M:1 nM (IC50), EGFR exon 20 ASV insertion:51.9 nM (IC50), Her2 exon 20 YVMA insertion:21.2 nM (IC50) |
Synonyms | N-[5-[[4-[5-Chloro-4-fluoro-2-(2-hydroxypropan-2-yl)anilino]pyrimidin-2-yl]amino]-2-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-4-methoxyphenyl]prop-2-enamide, DZD9008 |
Molecular Weight | 584.08 |
Formula | C29H35ClFN7O3 |
CAS No. | 2370013-49-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/ml (94.16 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
(S)-Sunvozertinib 2370013-49-1 Angiogenesis JAK/STAT signaling Tyrosine Kinase/Adaptors HER EGFR HER1 Her2 (S)Sunvozertinib mutant forms of ErbB Epidermal growth factor receptor lung DZD 9008 ErbB-1 DZD-9008 inhibit Btk breast cancer (S)-DZD9008 Inhibitor N-[5-[[4-[5-Chloro-4-fluoro-2-(2-hydroxypropan-2-yl)anilino]pyrimidin-2-yl]amino]-2-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-4-methoxyphenyl]prop-2-enamide Sunvozertinib Bruton tyrosine kinase DZD9008 (S) Sunvozertinib inhibitor