Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 91.00 | |
10 mg | In stock | $ 131.00 | |
25 mg | In stock | $ 261.00 | |
50 mg | In stock | $ 391.00 | |
100 mg | In stock | $ 587.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 100.00 |
Description | (Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis. |
In vitro | In HUVEC, Z-guggulsterone (10, 20 μM; 24 or 48 hours) induces a reduction in the level of VEGF-R2 protein [1]. |
In vivo | In tumor volume and wet tumor weight, Z-guggulsterone (p.o.; 1 mg; 5 times/week) causes a statistically significant reduction [1]. |
Molecular Weight | 312.45 |
Formula | C21H28O2 |
CAS No. | 39025-23-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (32.01 mM)
You can also refer to dose conversion for different animals. More
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(Z)-Guggulsterone 39025-23-5 Angiogenesis Apoptosis Cytoskeletal Signaling PI3K/Akt/mTOR signaling Tyrosine Kinase/Adaptors Akt VEGFR inhibit Protein kinase B PKB Inhibitor Guggulsterone (Z) Guggulsterone Vascular endothelial growth factor receptor (Z)Guggulsterone inhibitor