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(R)-Trolox

Name: (R)-Trolox
Brand: TargetMol
SKU: T12645
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T12645Cas No. 53101-49-8

(R)-Trolox is a water soluble vitamin E analogue and a competitive tyrosinase inhibitor (Ki value of 0.83 mM and a ID50 value of 1.88 mM).

(R)-Trolox

🥰Excellent

Catalog No. T12645Cas No. 53101-49-8

(R)-Trolox is a water soluble vitamin E analogue and a competitive tyrosinase inhibitor (Ki value of 0.83 mM and a ID50 value of 1.88 mM).

Pack Size	Price	Availability
50 mg	$39	In Stock
100 mg	$55	In Stock
1 mL x 10 mM (in DMSO)	$43	In Stock

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Product Introduction

Bioactivity

Description	(R)-Trolox is a water soluble vitamin E analogue and a competitive tyrosinase inhibitor (Ki value of 0.83 mM and a ID50 value of 1.88 mM).
In vitro	The inhibition of DMSO on the mushroom tyrosinase is dosedependent. Additions of DMSO at the two levels in the tyrosinase digests containing (R)-Trolox ((R)-HTCCA) results in further inhibitions of the tyrosinase activity. The influence of the DMSO on the inhibitory effects of (R)-Trolox against the tyrosinase is also dose-dependent.

Chemical Properties

Molecular Weight	250.29
Formula	C₁₄H₁₈O₄
Cas No.	53101-49-8
Smiles	Cc1c(C)c2O[C@](C)(CCc2c(C)c1O)C(O)=O
Relative Density.	1.219 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 250 mg/mL (998.84 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9954 mL	19.9768 mL	39.9537 mL	199.7683 mL
5 mM	0.7991 mL	3.9954 mL	7.9907 mL	39.9537 mL
10 mM	0.3995 mL	1.9977 mL	3.9954 mL	19.9768 mL
20 mM	0.1998 mL	0.9988 mL	1.9977 mL	9.9884 mL
50 mM	0.0799 mL	0.3995 mL	0.7991 mL	3.9954 mL
100 mM	0.0400 mL	0.1998 mL	0.3995 mL	1.9977 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

(R) Trolox(R)TroloxTrolox