Powder: -20°C for 3 years | In solvent: -80°C for 1 year
α-Zearalenol is one of the major metabolites of Zearalenone. α-Zearalenol has structural analogy to estrogen, thus α-Zearalenol can bind to estrogen receptors (ERs).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 108.00 | |
5 mg | In stock | $ 228.00 | |
10 mg | In stock | $ 347.00 | |
25 mg | Inquiry | $ 578.00 | |
50 mg | Inquiry | $ 825.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 253.00 |
Description | α-Zearalenol is one of the major metabolites of Zearalenone. α-Zearalenol has structural analogy to estrogen, thus α-Zearalenol can bind to estrogen receptors (ERs). |
In vitro | α-Zearalenol (0.001-10 μM; 24-72 hours) shows the highest RPE (90.5%) at 9.37 μM α-ZOL exposure in MFC-7 cells (IC50: 12.5 μM) [1].α-Zearalenol (0.001-10 μM; 24-72 hours) induces an increase of cell viability on MCF-7 cells mainly after 72 h of treatment whereas it is slightly cytotoxic on MDA-MB231 cells. It increases the MCF7 cell population in the S phase and in the G2/M phase, no visible change in cell cycle phases is observed in MDA-MB231 cells. α-Zearalenol (1-10 μM; 24 hours) reduces the expression of TNF-α, α-Zearalenol combines with β-ZOL shows an antagonistic effect on inflammation for IL-1β and act synergically for IL-8 at high toxin concentrations [2]. |
Molecular Weight | 320.38 |
Formula | C18H24O5 |
CAS No. | 36455-72-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (187.28 mM)
You can also refer to dose conversion for different animals. More
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α-Zearalenol 36455-72-8 Endocrinology/Hormones Estrogen Receptor/ERR Inhibitor α Zearalenol a-Zearalenol αZearalenol alpha-Zearalenol inhibit inhibitor