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Pack Size | Price | Availability | Quantity |
---|---|---|---|
500 μg | $140 | 35 days | |
1 mg | $263 | 35 days | |
5 mg | $1,070 | 35 days |
Description | Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2α are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor Prostaglandin F2α (16-phenoxy tetranor PGF2α) is a metabolically stable form of PGF2α containing a 16-phenoxy group at the ω-terminus. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2α. 16-phenoxy tetranor PGF2α methyl ester is a lipophilic analog of 16-phenoxy tetranor PGF2α. Methyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid. |
Alias | 16-phenoxy tetranor Prostaglandin F2α methyl ester |
Molecular Weight | 404.503 |
Formula | C23H32O6 |
Cas No. | 51638-90-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility Information | DMSO: 100 mg/mL Ethanol: 100 mg/mL PBS (pH 7.2): 0.5 mg/mL DMF: 100 mg/mL |
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