Powder: -20°C for 3 years | In solvent: -80°C for 1 year
17α-Hydroxyprogesterone (17-OHP) is a physiological progestin that is produced during glucocorticoid and steroid hormone synthesis and is increased during the third trimester of pregnancy. Hydroxyprogesterone binds to the cytoplasmic progesterone receptors in the reproductive system and subsequently activates progesterone receptor-mediated gene expression.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 g | In stock | $ 25.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 28.00 |
Description | 17α-Hydroxyprogesterone (17-OHP) is a physiological progestin that is produced during glucocorticoid and steroid hormone synthesis and is increased during the third trimester of pregnancy. Hydroxyprogesterone binds to the cytoplasmic progesterone receptors in the reproductive system and subsequently activates progesterone receptor-mediated gene expression. |
In vitro | 17α-OHP is an agonist of the progesterone receptor (PR) similarly to progesterone, albeit weakly in comparison[1]. It is a chemical intermediate in the biosynthesis of steroid hormones, including the androgen and estrogen sex hormones and the glucocorticoids and mineralocorticoids. |
In vivo | 17-Hydroxyprogesterone is a potent steroid inducer of GVBD (germinal vesicle breakdown)[3]. |
Synonyms | Hydroxyprogesterone, 17-OHP, 17-Hydroxyprogesterone |
Molecular Weight | 330.46 |
Formula | C21H30O3 |
CAS No. | 68-96-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 38 mg/mL (115 mM)
Ethanol: 61 mg/mL (184.6 mM)
You can also refer to dose conversion for different animals. More
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17α-Hydroxyprogesterone 68-96-2 Endocrinology/Hormones Metabolism Others Progesterone Receptor Estrogen/progestogen Receptor Endogenous Metabolite 17alpha-Hydroxyprogesterone Hydroxyprogesterone NR3C3 17-OHP Inhibitor 17-Hydroxyprogesterone inhibit 17a-Hydroxyprogesterone 17α Hydroxyprogesterone 17αHydroxyprogesterone inhibitor