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17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester

Catalog No. T37947 CAS 195503-20-9

Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. 17-trifluoromethylphenyl trinor PGF2α is an analog of PGF2α that shares the meta-trifluoromethyl group of travoprost with the 17-phenyl trinor modification of latanoprost. It is anticipated to be a potent and selective agonist of the FP receptor, with potential applications in glaucoma and luteolysis. 17-trifluoromethylphenyl trinor PGF2α methyl ester is a lipophilic analog of 17-trifluoromethylphenyl trinor PGF2α. Methyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.

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17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester, CAS 195503-20-9

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	470.529
Formula	C25H33F3O5
CAS No.	195503-20-9

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

PBS (pH 7.2): 0.15 mg/mL

DMF: 25 mg/mL

Ethanol: 50 mg/mL

DMSO: 50 mg/mL

( < 1 mg/ml refers to the product slightly soluble or insoluble )

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Keywords

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