Powder: -20°C for 3 years | In solvent: -80°C for 1 year
2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a second messenger in cellular innate immunity and is catalyzed by cGAMP synthase (cGAS) under DNA binding conditions. 2',3'-cGAMP binds to STING to form a dimer, inducing the production and expression of interferon-β and other cytokines.
Description | 2',3'-cGAMP (2'-3'-cyclic GMP-AMP) is a second messenger in cellular innate immunity and is catalyzed by cGAMP synthase (cGAS) under DNA binding conditions. 2',3'-cGAMP binds to STING to form a dimer, inducing the production and expression of interferon-β and other cytokines. |
Synonyms | 2'-3'-cyclic GMP-AMP |
Molecular Weight | 674.417 |
Formula | C20H24N10O13P2 |
CAS No. | 1441190-66-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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2',3'-cGAMP 1441190-66-4 Immunology/Inflammation STING cGAS 2',3'cGAMP 2',3' cGAMP 2'-3'-cyclic GMP-AMP inhibitor inhibit