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2,5-Dihydroxybenzaldehyde

Catalog No. TN2730 CAS 1194-98-5

Synonyms: 2,5-二羟基苯甲醛, Gentisaldehyde

2,5-Dihydroxybenzaldehyde has antioxidant activity against Mycobacterium avium subsp. Paratuberculosis. 2,5-Dihydroxybenzaldehyde also inhibits S. aureus strains(MIC50: 500 mg/L).

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2,5-Dihydroxybenzaldehyde, CAS 1194-98-5

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	2,5-Dihydroxybenzaldehyde has antioxidant activity against Mycobacterium avium subsp. Paratuberculosis. 2,5-Dihydroxybenzaldehyde also inhibits S. aureus strains(MIC50: 500 mg/L).
Targets&IC50	S. aureus strains:500 mg/L(MIC50)
In vitro	2,5-Dihydroxybenzaldehyde modified the three lipid monolayer structures by integrating into the monolayer, forming aggregates of antimicrobial -lipid complexes, reducing the packing effectiveness of the lipids, increasing the membrane fluidity, and altering the total dipole moment in the monolayer membrane model. The interactions of 2,5-Dihydroxybenzaldehyde with bacterial phospholipids depended on both the structure of the antimicrobials and the composition of the monolayers[1].

Synonyms	2,5-二羟基苯甲醛, Gentisaldehyde
Molecular Weight	138.12
Formula	C7H6O3
CAS No.	1194-98-5

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 30 mg/ml (217.20 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Nowotarska SW, et al. Effect of structure on the interactions between five natural antimicrobial compounds and phospholipids of bacterial cell membrane on model monolayers. Molecules. 2014 Jun 6;19(6):7497-515. 2. Bisht GS, et al. Diffusion-free mediator based miniature biofuel cell anode fabricated on a carbon-MEMS electrode. Langmuir. 2012 Oct 2;28(39):14055-64. 3. Schabauer A, et al. Gentisaldehyde and Its Derivative 2,3-Dihydroxybenzaldehyde Show Antimicrobial Activities Against Bovine Mastitis Staphylococcus aureus. Front Vet Sci. 2018 Jul 11;5:148.

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Keywords

2,5-Dihydroxybenzaldehyde 1194-98-5 微生物学 Antibacterial Anti-infection 2,5Dihydroxybenzaldehyde inhibit mastitis 2,5 Dihydroxybenzaldehyde antiseptic phosphate Bacterial ions Antimicrobial S. aureus Bovine Inhibitor Gentisaldehyde inhibitor

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