Powder: -20°C for 3 years | In solvent: -80°C for 1 year
2-Iodomelatonin is a potent agonist of melatonin receptor 1 (MT1) with a Ki value of 28 pM, it is more 5-fold selective for MT1 over MT2. 2-iodomelatonin can be used to identify, characterize and localize melatonin binding sites in the brain and peripheral tissues.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 39.00 | |
10 mg | In stock | $ 64.00 | |
25 mg | In stock | $ 128.00 | |
50 mg | In stock | $ 213.00 | |
100 mg | In stock | $ 347.00 | |
200 mg | In stock | $ 516.00 | |
500 mg | In stock | $ 825.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 43.00 |
Description | 2-Iodomelatonin is a potent agonist of melatonin receptor 1 (MT1) with a Ki value of 28 pM, it is more 5-fold selective for MT1 over MT2. 2-iodomelatonin can be used to identify, characterize and localize melatonin binding sites in the brain and peripheral tissues. |
In vitro | 2-iodomelatonin (0-7.5 μM; 18 hours) shares the protective properties of melatonin, it inhibits cell death of mutant htt ST14A and inhibits the increase in Rip2 expression in stressed mutant htt ST14A cells[1]. |
Molecular Weight | 358.17 |
Formula | C13H15IN2O2 |
CAS No. | 93515-00-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 27 mg/mL (75.4 mM), Sonification and heating are recommended.
You can also refer to dose conversion for different animals. More
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2-Iodomelatonin 93515-00-5 GPCR/G Protein Melatonin Receptor 2Iodomelatonin 2 Iodomelatonin inhibitor inhibit