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3-Hydroxyanthranilic acid

Catalog No. T4707   CAS 548-93-6
Synonyms: 3-HYDROXY-2-AMINOBENZOIC ACID

3-Hydroxyanthranilic acid (3-HYDROXY-2-AMINOBENZOIC ACID), also known as 2-amino-3-hydroxy-benzoate or 3-ohaa, belongs to the class of organic compounds known as hydroxybenzoic acid derivatives. 3-Hydroxyanthranilic acid has been found in human epidermis and bladder tissues, and has also been detected in multiple biofluids, such as urine and blood. Within the cell, 3-hydroxyanthranilic acid is primarily located in the cytoplasm. 3-Hydroxyanthranilic acid exists in all eukaryotes, ranging from yeast to humans. 3-Hydroxyanthranilic acid participates in a number of enzymatic reactions. In particular, 3-Hydroxyanthranilic acid and L-alanine can be biosynthesized from L-3-hydroxykynurenine; which is catalyzed by the enzyme kynureninase. Furthermore, 3-Hydroxyanthranilic acid can be converted into cinnavalininate through its interaction with the enzyme catalase. Furthermore, L-Alanine and 3-hydroxyanthranilic acid can be biosynthesized from 3-hydroxy-L-kynurenine through its interaction with the enzyme kynureninase. Furthermore, 3-Hydroxyanthranilic acid can be converted into 2-amino-3-carboxymuconic acid semialdehyde; which is catalyzed by the enzyme 3-hydroxyanthranilate 3,4-dioxygenase. Furthermore, 3-Hydroxyanthranilic acid can be converted into 2-amino-3-carboxymuconic acid semialdehyde through the action of the enzyme 3-hydroxyanthranilate 3,4-dioxygenase. Finally, L-Alanine and 3-hydroxyanthranilic acid can be biosynthesized from 3-hydroxy-L-kynurenine; which is mediated by the enzyme kynureninase. In humans, 3-hydroxyanthranilic acid is involved in the tryptophan metabolism pathway.

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3-Hydroxyanthranilic acid Chemical Structure
3-Hydroxyanthranilic acid, CAS 548-93-6
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100 mg In stock $ 66.00
1 mL * 10 mM (in DMSO) In stock $ 45.00
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Purity: 99.98%
Purity: 99.49%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description 3-Hydroxyanthranilic acid (3-HYDROXY-2-AMINOBENZOIC ACID), also known as 2-amino-3-hydroxy-benzoate or 3-ohaa, belongs to the class of organic compounds known as hydroxybenzoic acid derivatives. 3-Hydroxyanthranilic acid has been found in human epidermis and bladder tissues, and has also been detected in multiple biofluids, such as urine and blood. Within the cell, 3-hydroxyanthranilic acid is primarily located in the cytoplasm. 3-Hydroxyanthranilic acid exists in all eukaryotes, ranging from yeast to humans. 3-Hydroxyanthranilic acid participates in a number of enzymatic reactions. In particular, 3-Hydroxyanthranilic acid and L-alanine can be biosynthesized from L-3-hydroxykynurenine; which is catalyzed by the enzyme kynureninase. Furthermore, 3-Hydroxyanthranilic acid can be converted into cinnavalininate through its interaction with the enzyme catalase. Furthermore, L-Alanine and 3-hydroxyanthranilic acid can be biosynthesized from 3-hydroxy-L-kynurenine through its interaction with the enzyme kynureninase. Furthermore, 3-Hydroxyanthranilic acid can be converted into 2-amino-3-carboxymuconic acid semialdehyde; which is catalyzed by the enzyme 3-hydroxyanthranilate 3,4-dioxygenase. Furthermore, 3-Hydroxyanthranilic acid can be converted into 2-amino-3-carboxymuconic acid semialdehyde through the action of the enzyme 3-hydroxyanthranilate 3,4-dioxygenase. Finally, L-Alanine and 3-hydroxyanthranilic acid can be biosynthesized from 3-hydroxy-L-kynurenine; which is mediated by the enzyme kynureninase. In humans, 3-hydroxyanthranilic acid is involved in the tryptophan metabolism pathway.
Synonyms 3-HYDROXY-2-AMINOBENZOIC ACID
Molecular Weight 153.14
Formula C7H7NO3
CAS No. 548-93-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 25 mg/mL (163.25 mM)

TargetMolReferences and Literature

1. Antoni A D , Rubaltelli F F , Costa C , et al. Effect of phototherapy on the urinary excretion of tryptophan metabolites in neonatal hyperbilirubinemia.[J]. Acta Vitaminologica Et Enzymologica, 1975, 29(1-6):145. 2. Calandra P . Research on tryptophan metabolites "via kynurenine" in epidermis of man and mouse.[J]. Acta Vitaminol Enzymol, 1975, 29(1-6):158-160. 3. Hegedus Z L , Frank H A , Altschule M D , et al. Human plasma lipofuscin melanins formed from tryptophan metabolites[J]. Archives Internationales de Physiologie, 1986, 94(5):10. 4. Werner E R , Lutz H , Fuchs D , et al. Identification of 3-Hydroxyanthranilic Acid in Mixed Lymphocyte Cultures[J]. Biological Chemistry, 1985, 366(1):99-102. 5. Teulings F A , Mulderkooy G E , Peters H A , et al. The excretion of 3-hydroxyanthranilic acid in patients with bladder and kidney carcinoma.[J]. Acta Vitaminol Enzymol, 1975, 29(1-6):108-112.

Related compound libraries

This product is contained In the following compound libraries：
Human Endogenous Metabolite Library Natural Product Library for HTS Mouse Metabolite Compound Library RO5 Drug-like Natural Product Library Human Metabolite Library Human Endogenous Metabolite Compound Library Plus Natural Product Library

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Keywords

3-Hydroxyanthranilic acid 548-93-6 Metabolism Others Endogenous Metabolite 3 Hydroxyanthranilic acid 3-HYDROXY-2-AMINOBENZOIC ACID Inhibitor inhibit 3Hydroxyanthranilic acid inhibitor

 

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