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3-Hydroxyphenylacetic acid

Catalog No. T4829 CAS 621-37-4

3-Hydroxyphenylacetic acid is a rutin metabolite and an antioxidant. It has a protective biological activity in human. It is a substrate of enzyme 4-hydroxyphenylacetate 3-monooxygenase [EC 1.14.13.3] in the pathway tyrosine metabolism. 3-Hydroxyphenylacetic acid is found to be associated with phenylketonuria, which is an inborn error of metabolism.

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3-Hydroxyphenylacetic acid Chemical Structure

3-Hydroxyphenylacetic acid, CAS 621-37-4

Pack Size	Availability	Price/USD	Quantity
100 mg	In stock	$ 42.00
1 mL * 10 mM (in DMSO)	In stock	$ 46.00

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Purity: 98.21%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	152.15
Formula	C8H8O3
CAS No.	621-37-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/mL (361.49 mM)

References and Literature

1. Young S N , Davis B A , Gauthier S . Precursors and metabolites of phenylethylamine, m and p-tyramine and tryptamine in human lumbar and cisternal cerebrospinal fluid.[J]. Journal of Neurology Neurosurgery & Psychiatry, 1982, 45(7):633-9. 2. Davis B A , Durden D A , Boulton A A . Plasma concentrations of p- and m-hydroxyphenylacetic acid and phenylacetic acid in humans: gas chromatographic--high-resolution mass spectrometric analysis.[J]. J Chromatogr, 1982, 230(2):219-230. 3. Davis B A , Boulton A A . Longitudinal urinary excretion of some "trace" acids in a human male[J]. Journal of Chromatography, 1981, 222(2):161-169. 4. Nahmias C , Wahl L M , Amano S , et al. Chirakal R. Equilibration of 6-[18F]fluoro-L-m-tyrosine between plasma and erythrocytes[J]. Journal of Nuclear Medicine Official Publication Society of Nuclear Medicine, 2000, 41(10):1636. 5. Baba S , Furuta T , Horie M , et al. Studies on drug metabolism by use of isotopes XXVI: Determination of urinary metabolites of rutin in humans[J]. Journal of Pharmaceutical Sciences, 2010, 70(7):780-782.

Related compound libraries

This product is contained In the following compound libraries：

Microbial Natural Product Library Tobacco Monomer Library Immunology/Inflammation Compound Library Ferroptosis Compound Library RO5 Drug-like Natural Product Library Antioxidant Compound Library Natural Product Library for HTS Human Metabolite Library Bioactive Compound Library Anti-Fibrosis Compound Library

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Keywords

3-Hydroxyphenylacetic acid 621-37-4 Metabolism Others Endogenous Metabolite 3Hydroxyphenylacetic acid 3 Hydroxyphenylacetic acid inhibit Inhibitor inhibitor

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