Powder: -20°C for 3 years | In solvent: -80°C for 1 year
3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a). Displays ≥ 40-fold selectivity over other receptors: mGluR-5, mGluR-2, mGluR-4 (mGluR-4a) (IC50 < 300 μM), NMDA and GluR (AMPA) (IC50 = 250 μM). 3-MATIDA act as a neuroprotectant in cultured murine cortical cells and rat hippocampal slice cultures in vitro.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 37.00 | |
2 mg | In stock | $ 50.00 | |
5 mg | In stock | $ 78.00 | |
10 mg | In stock | $ 127.00 | |
25 mg | In stock | $ 260.00 | |
50 mg | In stock | $ 423.00 | |
100 mg | In stock | $ 628.00 | |
500 mg | In stock | $ 1,350.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 78.00 |
Description | 3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a). Displays ≥ 40-fold selectivity over other receptors: mGluR-5, mGluR-2, mGluR-4 (mGluR-4a) (IC50 > 300 μM), NMDA and GluR (AMPA) (IC50 = 250 μM). 3-MATIDA act as a neuroprotectant in cultured murine cortical cells and rat hippocampal slice cultures in vitro. |
Targets&IC50 | mGluR-1:6.3 μM, mGluR-5:> 300 μM, GluR(AMPA):250 μM, mGluR-4:> 300 μM, mGluR-2:> 300 μM, NMDA:250 μM |
Molecular Weight | 215.23 |
Formula | C8H9NO4S |
CAS No. | 518357-51-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mM
1eq. NaOH: 50 mM
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
3-MATIDA 518357-51-2 Neuroscience GluR NMDAR 3 MATIDA 3MATIDA inhibitor inhibit