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3-O-Acetyl-11-hydroxy-beta-boswellic acid

Catalog No. TN1255   CAS 146019-25-2

3-O-Acetyl-11-hydroxy-beta-boswellic acid is the precursor of 3-O-acetyl-9, 11-dehydro-beta-boswellic acid(a 5-lipoxygenase inhibitor ).

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3-O-Acetyl-11-hydroxy-beta-boswellic acid Chemical Structure
3-O-Acetyl-11-hydroxy-beta-boswellic acid, CAS 146019-25-2
Pack Size Availability Price/USD Quantity
1 mg In stock $ 129.00
5 mg In stock $ 313.00
10 mg In stock $ 497.00
25 mg In stock $ 793.00
50 mg In stock $ 1,080.00
1 mL * 10 mM (in DMSO) In stock $ 397.00
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Purity: 98.24%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description 3-O-Acetyl-11-hydroxy-beta-boswellic acid is the precursor of 3-O-acetyl-9, 11-dehydro-beta-boswellic acid(a 5-lipoxygenase inhibitor ).
In vitro 4 pentacyclic triterpenoid acids were isolated from Boswellia carterii and identified by NMR and Mass spectroscopic analysis (compounds 1, 3-O-acetyl-9,11-dehydro-β-boswellic acid; 2, 3-O-Acetyl-11-hydroxy-beta-boswellic acid ; 3. 3-O- acetyl-11-keto-β-boswellic acid and 4, 11-keto-β-boswellic acid. Their inhibitory activity on Jack bean urease were evaluated. Docking and pharmacophore analysis using AutoDock 4.2 and Ligandscout 3.03 programs were also performed to explain possible mechanism of interaction between isolated compounds and urease enzyme. It was found that compound 1 has the strongest inhibitory activity against Jack bean urease (IC50 = 6.27 ± 0.03 μM), compared with thiourea as a standard inhibitor (IC50 = 21.1 ± 0.3 μM)[1]
Source
Molecular Weight 514.74
Formula C32H50O5
CAS No. 146019-25-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (97.14 mM)

TargetMolReferences and Literature

1. Golbabaei S, et al. Urease inhibitory activities of β-boswellic acid derivatives. Daru. 2013 Jan 2;21(1):2.

Related compound libraries

This product is contained In the following compound libraries:
NO PAINS Compound Library Bioactive Compound Library Anti-Obesity Compound Library Natural Product Library Terpene Natural Product Library Inhibitor Library Bioactive Compounds Library Max Traditional Chinese Medicine Monomer Library PBCRBS Traditional Chinese Medicine Compound Library Selected Plant-Sourced Compound Library

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Keywords

3-O-Acetyl-11-hydroxy-beta-boswellic acid 146019-25-2 Metabolism Lipoxygenase 3OAcetyl11hydroxybetaboswellic acid LOX Inhibitor 3-O-Acetyl-11-hydroxy-b-boswellic acid 3-O-Acetyl-11-hydroxy-β-boswellic acid 3 O Acetyl 11 hydroxy beta boswellic acid inhibit inhibitor

 

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