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4-Methyldaphnetin

Catalog No. TJS0315 CAS 2107-77-9

Synonyms: 7,8-Dihydroxy-4-methylcoumarin, DHMC

4-Methyldaphnetin (DHMC) is a potent inhibitor (low micromolar) of lipid peroxidation and scavengers of superoxide anion radicals and of aqueous alkylperoxyl radicals, but may be pro-oxidant (enhancing generation of hydroxyl radicals) in the presence of free iron ions.2. 4-Methyldaphnetin(7,8-Dihydroxy-4-methylcoumarin) inhibits the proinflammatory 5-lipoxygenase enzyme at micromolar concentrations.

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4-Methyldaphnetin, CAS 2107-77-9

Pack Size	Availability	Price/USD
5 mg	In stock	$ 39.00
10 mg	In stock	$ 57.00
25 mg	In stock	$ 94.00
50 mg	In stock	$ 138.00
100 mg	In stock	$ 198.00
1 mL * 10 mM (in DMSO)	In stock	$ 37.00

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Purity: 99.57%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Source

Natural Products > Fabaceae > Glycine

Synonyms	7,8-Dihydroxy-4-methylcoumarin, DHMC
Molecular Weight	192.17
Formula	C10H8O4
CAS No.	2107-77-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble

DMSO: 35 mg/mL(182.1 mM)

References and Literature

1. Hoult J R S , Miguel Pay¨¢. Pharmacological and biochemical actions of simple coumarins: Natural products with therapeutic potential[J]. General Pharmacology the Vascular System, 1996, 27(4):713-722.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Active Compound Library Inhibitor Library Metabolism Compound Library Anti-Tumor Natural Product Library Apoptosis Compound Library RO5 Drug-like Natural Product Library Ferroptosis Compound Library Target-Focused Phenotypic Screening Library Lipid Metabolism Compound Library Traditional Chinese Medicine Monomer Library

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Keywords

4-Methyldaphnetin 2107-77-9 Apoptosis Metabolism Lipoxygenase 7,8-Dihydroxy-4-methylcoumarin inhibit DHMC Inhibitor 4Methyldaphnetin 4 Methyldaphnetin inhibitor

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