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5,​7,​4'-​Trimethoxyflavone

Catalog No. T8296   CAS 5631-70-9
Synonyms: 4',5,7-Trimethoxyflavone

5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
5,​7,​4'-​Trimethoxyflavone Chemical Structure
5,​7,​4'-​Trimethoxyflavone, CAS 5631-70-9
Pack Size Availability Price/USD Quantity
1 mg In stock $ 41.00
5 mg In stock $ 90.00
10 mg In stock $ 130.00
25 mg In stock $ 215.00
50 mg In stock $ 318.00
100 mg In stock $ 469.00
1 mL * 10 mM (in DMSO) In stock $ 100.00
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Purity: 97.53%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description 5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.
In vitro 5,7,4'-Trimethoxyflavone induces apoptosis, as evidenced by increments of sub-G1 phase, DNA fragmentation, annexin-V/PI staining, the Bax/Bcl-xL ratio, proteolytic activation of caspase-3, and degradation of PARP protein. 5,7,4'-Trimethoxyflavone is significantly effective at inhibiting the proliferation of SNU-16 human gastric cancer cells in a concentration-dependent manner.
Source
Synonyms 4',5,7-Trimethoxyflavone
Molecular Weight 312.32
Formula C18H16O5
CAS No. 5631-70-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 22.5 mg/mL (72.04 mM)

TargetMolReferences and Literature

1. Kim H, et al. Induction of ER Stress-Mediated Apoptosis by the Major Component 5,7,4'-TrimethoxyflavoneIsolated from Kaempferia parviflora Tea Infusion. Nutr Cancer. 2018 Aug-Sep;70(6):984-996.

Related compound libraries

This product is contained In the following compound libraries：
DNA Damage & Repair Compound Library Bioactive Compounds Library Max Traditional Chinese Medicine Monomer Library Traditional Mongolian Medicine Compound Library Tobacco Monomer Library Anti-Neurodegenerative Disease Compound Library Flavonoid Natural Product Library Food as Medicine Compound Library Bioactive Compound Library Anti-Cardiovascular Disease Compound Library

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Keywords

5,​7,​4'-​Trimethoxyflavone 5631-70-9 Apoptosis Chromatin/Epigenetic DNA Damage/DNA Repair Proteases/Proteasome PARP Caspase poly ADP ribose polymerase 5,​7,​4' ​Trimethoxyflavone inhibit 5,​7,​4'​Trimethoxyflavone 5,?7,?4'-?Trimethoxyflavone Inhibitor Endogenous Metabolite 4',5,7-Trimethoxyflavone 5,7,4'-Trimethoxyflavone inhibitor

 

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