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5-Benzyloxygramine

Catalog No. T35841 CAS 1453-97-0

5-Benzyloxygramine blocks the Dopamin receptors and antagonizes the effects of 5-HT on the rat uterus and the rabbit ear.

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5-Benzyloxygramine, CAS 1453-97-0

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Purity: 96.33%

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Description	5-Benzyloxygramine blocks the Dopamin receptors and antagonizes the effects of 5-HT on the rat uterus and the rabbit ear.
In vitro	5-Benzyloxygramine induces stabilization of N-NTD dimers via concurrent hydrophobic interactions with both entities, leading to irregular N protein oligomerization, a finding further substantiated in cellular studies[1].

Molecular Weight	280.36
Formula	C18H20N2O
CAS No.	1453-97-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 250 mg/mL (891.71 mM), Sonication is recommended.

References and Literature

1. Shan-Meng Lin, et al. Structure-Based Stabilization of Non-native Protein-Protein Interactions of Coronavirus Nucleocapsid Proteins in Antiviral Drug Design. J Med Chem. 2020 Mar 26;63(6):3131-3141.

Related compound libraries

This product is contained In the following compound libraries：

Membrane Protein-targeted Compound Library Anti-Neurodegenerative Disease Compound Library GPCR Compound Library Anti-Viral Compound Library Bioactive Compounds Library Max Neurotransmitter Receptor Compound Library Serotonin Receptor-Targeted Compound Library Bioactive Compound Library Neuronal Signaling Compound Library PPI Inhibitor Library

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Keywords

5-Benzyloxygramine 1453-97-0 GPCR/G Protein Neuroscience 5-HT Receptor Dopamine Receptor Inhibitor inhibit 5Benzyloxygramine 5 Benzyloxygramine inhibitor

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