Powder: -20°C for 3 years | In solvent: -80°C for 1 year
5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase (IC50s: 9, 20 and 25 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 6-8 weeks | $ 297.00 | |
25 mg | 6-8 weeks | $ 987.00 | |
50 mg | 6-8 weeks | $ 1,360.00 | |
100 mg | 6-8 weeks | $ 1,860.00 |
Description | 5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase (IC50s: 9, 20 and 25 nM). |
Targets&IC50 | CDK5-p25:20 nM, CDK1-CyclinB:25 nM, GSK-3β:9 nM |
Molecular Weight | 403.17 |
Formula | C16H10IN3O2 |
CAS No. | 331467-03-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 66.7 mg/mL (165.43 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
5-Iodo-indirubin-3'-monoxime 331467-03-9 Cell Cycle/Checkpoint PI3K/Akt/mTOR signaling Stem Cells GSK-3 CDK Glycogen synthase kinase-3 5Iodoindirubin3'monoxime Inhibitor Glycogen synthase kinase 3 Cyclin dependent kinase 5 Iodo indirubin 3' monoxime inhibit inhibitor